iPTMnet Report for Q96C10 (DHX58)
Protein Information
| UniProt AC / UniProt ID | Q96C10 / DHX58_HUMAN |
| Protein Name | ATP-dependent RNA helicase DHX58 |
| Gene Name | Name: DHX58 Synonyms:D11LGP2E,LGP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96C10 |
| PRO Name | ATP-dependent RNA helicase DHX58 (human) |
| Definition | An ATP-dependent RNA helicase DHX58 that is encoded in the genome of human. |
| Short Label | hDHX58 |
| Category | organism-gene |
Q96C10 (DHX58) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K18 | Acetylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K335 | Acetylation | score1 | PhosphoSitePlus | |||
| K350 | Acetylation | score1 | PhosphoSitePlus | |||
| C450 | Methylation | score1 | IEDB | 31844290 | ||
| Y518 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C450 | Y450 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y518 | C518 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y518 | H518 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
DAG View