Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96C10 / DHX58_HUMAN
Protein Name ATP-dependent RNA helicase DHX58
Gene Name Name: DHX58
Synonyms:D11LGP2E,LGP2;
Organism Homo sapiens (Human)

PRO ID PR:Q96C10
DAG View
PRO Name ATP-dependent RNA helicase DHX58 (human)
Definition An ATP-dependent RNA helicase DHX58 that is encoded in the genome of human.
Short Label hDHX58
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96C10 (DHX58) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K18 Acetylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
K335 Acetylation PhosphoSitePlus
K350 Acetylation PhosphoSitePlus
C450 Methylation IEDB 31844290
Y518 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C450 Y450 Biomuta DOID:363 / uterine cancer [ icgc ]
Y518 C518 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y518 H518 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]