iPTMnet Report for Q96BK5 (PINX1)
Protein Information
| UniProt AC / UniProt ID | Q96BK5 / PINX1_HUMAN |
| Protein Name | PIN2/TERF1-interacting telomerase inhibitor 1 |
| Gene Name | Name: PINX1 Synonyms:LPTL,LPTS; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96BK5 |
| PRO Name | PIN2/TERF1-interacting telomerase inhibitor 1 (human) |
| Definition | A pin2-interacting protein X1 that is encoded in the genome of human. |
| Short Label | hPINX1 |
| Category | organism-gene |
DAG ViewQ96BK5 (PINX1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R7 | Methylation | score1 | PhosphoSitePlus | |||
| K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score3 | PhosphoSitePlus Signor | 20573420 | ||
| S110 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 20573420 | |
| S117 | Phosphorylation | score3 | PhosphoSitePlus Signor | 20573420 | ||
| S117 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 20573420 | |
| Y126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| T141 | Phosphorylation | score3 | PhosphoSitePlus Signor | 20573420 | ||
| T141 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 20573420 | |
| S161 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T164 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T170 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T171 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S226 | Phosphorylation | score3 | PhosphoSitePlus Signor | 20573420 | ||
| S226 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 20573420 | |
| Y227 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K231 | Sumoylation | score1 | PhosphoSitePlus | |||
| K252 | Methylation | score1 | PhosphoSitePlus | |||
| T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T317 | Phosphorylation | score3 | PhosphoSitePlus Signor | 20573420 | ||
| T317 | Phosphorylation | P53350 (PLK1) | score3 | PhosphoSitePlus Signor | 20573420 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R7 | P7 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S110 | Y110 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S161 | R161 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| T170 | N170 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K252 | N252 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T317 | M317 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ] |
