iPTMnet Report for Q96BF3 (TMIGD2)
Protein Information
UniProt AC / UniProt ID | Q96BF3 / TMIG2_HUMAN |
Protein Name | Transmembrane and immunoglobulin domain-containing protein 2 precursor |
Gene Name | Name: TMIGD2 Synonyms:CD28H,IGPR1;ORFNames:UNQ3059/PRO9879; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96BF3 |
PRO Name | transmembrane and immunoglobulin domain-containing protein 2 (human) |
Definition | A transmembrane and immunoglobulin domain-containing protein 2 that is encoded in the genome of human. |
Short Label | hTMIGD2 |
Category | organism-gene |
Q96BF3 (TMIGD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y192 | Phosphorylation | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S220 | Phosphorylation | P31749 (AKT1) | score4 | PhosphoSitePlus RLIMS-P Signor UniProt | 27838321, 31341021, 28920928, ... | |
Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
T224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S266 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y193 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y193 | C193 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y193 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y197 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y197 | C197 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T224 | S224 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S238 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
S262 | F262 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |