iPTMnet Report for Q96BF3 (TMIGD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BF3 / TMIG2_HUMAN
Protein Name Transmembrane and immunoglobulin domain-containing protein 2 precursor
Gene Name Name: TMIGD2
Synonyms:CD28H,IGPR1;ORFNames:UNQ3059/PRO9879;
Organism Homo sapiens (Human)

PRO ID PR:Q96BF3
DAG View
PRO Name transmembrane and immunoglobulin domain-containing protein 2 (human)
Definition A transmembrane and immunoglobulin domain-containing protein 2 that is encoded in the genome of human.
Short Label hTMIGD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BF3 (TMIGD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S186 Phosphorylation PhosphoSitePlus
Y192 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor   UniProt 27838321, 31341021, 28920928, ...32978258, 19690332
S220 Phosphorylation P31749 (AKT1) Signor 31341021
Y222 Phosphorylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S183 Phosphorylation PhosphoSitePlus
Y188 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y193 C193 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y193 * Biomuta DOID:3571 / liver cancer [ cosmic ]
Y197 * Biomuta DOID:3571 / liver cancer [ cosmic ]
Y197 C197 Biomuta DOID:1324 / lung cancer [ cosmic ]
T224 S224 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S238 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S262 F262 Biomuta DOID:4159 / skin cancer [ cosmic ]