iPTMnet Report for Q93084 (ATP2A3)
Protein Information
UniProt AC / UniProt ID | Q93084 / AT2A3_HUMAN |
Protein Name | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
Gene Name | Name: ATP2A3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q93084 |
PRO Name | sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (human) |
Definition | A sarcoplasmic/endoplasmic reticulum calcium ATPase 3 that is encoded in the genome of human. |
Short Label | hATP2A3 |
Category | organism-gene |
Q93084 (ATP2A3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 12665801 | ||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
C268 | Methylation | score1 | IEDB | 31844290 | ||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
C364 | S-Nitrosylation | score0 | dbSNO | 2212679, 22126794 | ||
Y427 | Phosphorylation | score1 | PhosphoSitePlus | |||
K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
T441 | Phosphorylation | score1 | PhosphoSitePlus | |||
K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
K476 | Ubiquitination | score1 | PhosphoSitePlus | |||
K481 | Acetylation | score1 | PhosphoSitePlus | |||
K481 | Ubiquitination | score1 | PhosphoSitePlus | |||
T484 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
C498 | S-Nitrosylation | score0 | dbSNO | 2212679 | ||
T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
K511 | Ubiquitination | score1 | PhosphoSitePlus | |||
K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
T534 | O-Glycosylation | score3 | GlyGen | 35469018, 29351928 | ||
T538 | Phosphorylation | score1 | PhosphoSitePlus | |||
K548 | Ubiquitination | score1 | PhosphoSitePlus | |||
T558 | Phosphorylation | score1 | PhosphoSitePlus | |||
K573 | Ubiquitination | score1 | PhosphoSitePlus | |||
K629 | Ubiquitination | score1 | PhosphoSitePlus | |||
K651 | Ubiquitination | score1 | PhosphoSitePlus | |||
S662 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
K684 | Ubiquitination | score1 | PhosphoSitePlus | |||
K712 | Ubiquitination | score1 | PhosphoSitePlus | |||
K713 | Ubiquitination | score1 | PhosphoSitePlus | |||
S755 | Phosphorylation | score1 | PhosphoSitePlus | |||
K758 | Ubiquitination | score1 | PhosphoSitePlus | |||
S823 | Phosphorylation | score1 | PhosphoSitePlus | |||
K875 | Ubiquitination | score1 | PhosphoSitePlus | |||
K999 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S1005 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K205 | E205 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S346 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
K431 | N431 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K436 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T499 | M499 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T534 | S534 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K573 | N573 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K712 | R712 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S823 | R823 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S1005 | L1005 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |