iPTMnet Report for Q93084 (ATP2A3)
Protein Information
| UniProt AC / UniProt ID | Q93084 / AT2A3_HUMAN |
| Protein Name | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 |
| Gene Name | Name: ATP2A3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q93084 |
| PRO Name | sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (human) |
| Definition | A sarcoplasmic/endoplasmic reticulum calcium ATPase 3 that is encoded in the genome of human. |
| Short Label | hATP2A3 |
| Category | organism-gene |
Q93084 (ATP2A3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 12665801 | ||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K205 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K252 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C268 | Methylation | score1 | IEDB | 31844290 | ||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C364 | S-Nitrosylation | score0 | dbSNO | 2212679, 22126794 | ||
| Y427 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K436 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K476 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K481 | Acetylation | score1 | PhosphoSitePlus | |||
| K481 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T484 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K492 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C498 | S-Nitrosylation | score0 | dbSNO | 2212679 | ||
| T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K511 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T534 | O-Glycosylation | score3 | GlyGen | 35469018, 29351928 | ||
| T538 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K548 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T558 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K573 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K629 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K651 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S662 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
| K684 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K712 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K713 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S755 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K758 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S823 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K875 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K999 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S1005 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K205 | E205 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S346 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| K431 | N431 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K436 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T499 | M499 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T534 | S534 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K573 | N573 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K712 | R712 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S823 | R823 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S1005 | L1005 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View