iPTMnet Report for Q92947 (GCDH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q92947 / GCDH_HUMAN
Protein Name Glutaryl-CoA dehydrogenase, mitochondrial precursor
Gene Name Name: GCDH
Organism Homo sapiens (Human)

PRO ID PR:Q92947
DAG View
PRO Name glutaryl-CoA dehydrogenase, mitochondrial (human)
Definition A glutaryl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hGCDH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q92947 (GCDH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
R88 Methylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
R319 Methylation PhosphoSitePlus
C350 Methylation IEDB 31844290
K361 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K438 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S246 Phosphorylation HPRD 20068231
T429 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S246 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R88 H88 Biomuta DOID:3565 / meningioma [ cosmic ]
S246 L246 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S255 W255 Biomuta DOID:4159 / skin cancer [ cosmic ]
R319 K319 Biomuta DOID:4159 / skin cancer [ cosmic ]