iPTMnet Report for Q92947 (GCDH)
Protein Information
UniProt AC / UniProt ID | Q92947 / GCDH_HUMAN |
Protein Name | Glutaryl-CoA dehydrogenase, mitochondrial precursor |
Gene Name | Name: GCDH |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92947 |
PRO Name | glutaryl-CoA dehydrogenase, mitochondrial (human) |
Definition | A glutaryl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human. |
Short Label | hGCDH |
Category | organism-gene |
Q92947 (GCDH) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
R88 | Methylation | score1 | PhosphoSitePlus | |||
K163 | Ubiquitination | score1 | PhosphoSitePlus | |||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
S255 | Phosphorylation | score1 | PhosphoSitePlus | |||
R319 | Methylation | score1 | PhosphoSitePlus | |||
C350 | Methylation | score1 | IEDB | 31844290 | ||
K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
K377 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y398 | Phosphorylation | score1 | PhosphoSitePlus | |||
K438 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R88 | H88 | Biomuta | DOID:3565 / meningioma [ cosmic ] | |
S246 | L246 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S255 | W255 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R319 | K319 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |