iPTMnet Report for Q92800 (EZH1)
Protein Information
UniProt AC / UniProt ID | Q92800 / EZH1_HUMAN |
Protein Name | Histone-lysine N-methyltransferase EZH1 |
Gene Name | Name: EZH1 Synonyms:KIAA0388; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92800 |
PRO Name | histone-lysine N-methyltransferase EZH1 (human) |
Definition | A histone-lysine N-methyltransferase EZH1 that is encoded in the genome of human. |
Short Label | hEZH1 |
Category | organism-gene |
Q92800 (EZH1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y319 | Phosphorylation | score1 | PhosphoSitePlus | |||
S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
K570 | Ubiquitination | score1 | PhosphoSitePlus | |||
S665 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y697 | Phosphorylation | score1 | PhosphoSitePlus | |||
K714 | Ubiquitination | score1 | PhosphoSitePlus | |||
K736 | Methylation | score1 | PhosphoSitePlus | |||
K736 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S665 | N665 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |