iPTMnet Report for Q92800 (EZH1)
Protein Information
| UniProt AC / UniProt ID | Q92800 / EZH1_HUMAN |
| Protein Name | Histone-lysine N-methyltransferase EZH1 |
| Gene Name | Name: EZH1 Synonyms:KIAA0388; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92800 |
| PRO Name | histone-lysine N-methyltransferase EZH1 (human) |
| Definition | A histone-lysine N-methyltransferase EZH1 that is encoded in the genome of human. |
| Short Label | hEZH1 |
| Category | organism-gene |
Q92800 (EZH1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y319 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S416 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K570 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S665 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y697 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K714 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K736 | Methylation | score1 | PhosphoSitePlus | |||
| K736 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S665 | N665 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View