iPTMnet Report for Q92743 (HTRA1)
Protein Information
| UniProt AC / UniProt ID | Q92743 / HTRA1_HUMAN |
| Protein Name | Serine protease HTRA1 precursor |
| Gene Name | Name: HTRA1 Synonyms:HTRA,PRSS11; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q92743 |
| PRO Name | serine protease HTRA1 (human) |
| Definition | A serine protease HTRA1 that is encoded in the genome of human. |
| Short Label | hHTRA1 |
| Category | organism-gene |
DAG ViewQ92743 (HTRA1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K168 | Acetylation | score1 | PhosphoSitePlus | |||
| S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S456 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K168 | N168 | Biomuta | [ cosmic ] | |
| Y238 | H238 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T365 | M365 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S456 | I456 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
