iPTMnet Report for Q92526 (CCT6B)
Protein Information
UniProt AC / UniProt ID | Q92526 / TCPW_HUMAN |
Protein Name | T-complex protein 1 subunit zeta-2 |
Gene Name | Name: CCT6B |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q92526 |
PRO Name | T-complex protein 1 subunit zeta-2 (human) |
Definition | A T-complex protein 1 subunit zeta-2 that is encoded in the genome of human. |
Short Label | hCCT6B |
Category | organism-gene |
Q92526 (CCT6B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R35 | Methylation | score1 | PhosphoSitePlus | |||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y109 | Phosphorylation | score1 | PhosphoSitePlus | |||
K144 | Acetylation | score1 | PhosphoSitePlus | |||
Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
S246 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y250 | Phosphorylation | score1 | PhosphoSitePlus | |||
K265 | Acetylation | score1 | PhosphoSitePlus | |||
K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Acetylation | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
S304 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K45 | E45 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K241 | Q241 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K265 | N265 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K295 | T295 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S301 | F301 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic ] | |
S304 | Y304 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S304 | F304 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |