Protein Information

Cytoscape View

UniProt AC / UniProt ID Q92526 / TCPW_HUMAN
Protein Name T-complex protein 1 subunit zeta-2
Gene Name Name: CCT6B
Organism Homo sapiens (Human)

PRO ID PR:Q92526
DAG View
PRO Name T-complex protein 1 subunit zeta-2 (human)
Definition A T-complex protein 1 subunit zeta-2 that is encoded in the genome of human.
Short Label hCCT6B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q92526 (CCT6B) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R35 Methylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
K265 Acetylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K295 Acetylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K45 E45 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K265 N265 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K295 T295 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K295 N295 Biomuta DOID:363 / uterine cancer [ tcga ]
S304 F304 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]