iPTMnet Report for Q8WZ75 (ROBO4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WZ75 / ROBO4_HUMAN
Protein Name Roundabout homolog 4 precursor
Gene Name Name: ROBO4
ORFNames:UNQ421/PRO3674;
Organism Homo sapiens (Human)

PRO ID PR:Q8WZ75
DAG View
PRO Name roundabout homolog 4 (human)
Definition A roundabout homolog 4 that is encoded in the genome of human.
Short Label hROBO4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WZ75 (ROBO4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
T232 O-Glycosylation GlyGen 30459171
N246 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490, ...30237853
S539 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
S656 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S805 Phosphorylation PhosphoSitePlus   UniProt 24275569
S938 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S539 Phosphorylation HPRD 18452278
S542 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T204 A204 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S542 N542 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S542 I542 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S561 F561 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S684 N684 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S938 F938 Biomuta DOID:4159 / skin cancer [ cosmic ]