iPTMnet Report for Q8WZ75 (ROBO4)
Protein Information
UniProt AC / UniProt ID | Q8WZ75 / ROBO4_HUMAN |
Protein Name | Roundabout homolog 4 precursor |
Gene Name | Name: ROBO4 ORFNames:UNQ421/PRO3674; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WZ75 |
PRO Name | roundabout homolog 4 (human) |
Definition | A roundabout homolog 4 that is encoded in the genome of human. |
Short Label | hROBO4 |
Category | organism-gene |
Q8WZ75 (ROBO4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
T204 | Phosphorylation | score1 | PhosphoSitePlus | |||
S212 | Phosphorylation | score1 | PhosphoSitePlus | |||
T232 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
N246 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 23090970, 19139490, ... | ||
S539 | Phosphorylation | score1 | PhosphoSitePlus | |||
S542 | Phosphorylation | score1 | PhosphoSitePlus | |||
S561 | Phosphorylation | score1 | PhosphoSitePlus | |||
S656 | Phosphorylation | score1 | PhosphoSitePlus | |||
S665 | Phosphorylation | score1 | PhosphoSitePlus | |||
S684 | Phosphorylation | score1 | PhosphoSitePlus | |||
S805 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S938 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T204 | A204 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S542 | N542 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S542 | I542 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S561 | F561 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S684 | N684 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S938 | F938 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |