iPTMnet Report for Q8WXI9 (GATAD2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXI9 / P66B_HUMAN
Protein Name Transcriptional repressor p66-beta
Gene Name Name: GATAD2B
Synonyms:KIAA1150;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXI9
DAG View
PRO Name transcriptional repressor p66-beta (human)
Definition A transcriptional repressor p66-beta that is encoded in the genome of human.
Short Label hGATAD2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXI9 (GATAD2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T5 Phosphorylation PhosphoSitePlus
R10 Methylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus   UniProt 23186163
K30 Ubiquitination PhosphoSitePlus
K33 Sumoylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T120 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17322306, 21406692, ...23186163, 17081983, 15302935, 18452278, 19651622, 18669648, 19690332, 20068231
S122 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17322306, 21406692, ...23186163, 17081983, 15302935, 18452278, 19651622, 18669648, 19690332, 20068231
S129 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 15302935, 18452278, 19651622, 18669648, 19415658, 19690332, 20068231
S134 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18452278, 18669648, ...19690332, 20068231
S135 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 19690332, 19415658, 20068231
S140 Phosphorylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus   UniProt 23186163
S213 Phosphorylation HPRD   PhosphoSitePlus 20068231
S223 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
R249 Methylation PhosphoSitePlus
R264 Methylation PhosphoSitePlus
R277 Methylation PhosphoSitePlus
K281 Methylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
T287 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T288 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T289 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
C308 S-Nitrosylation dbSNO 26338901
T311 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 32938750, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T311 Phosphorylation PhosphoSitePlus
S313 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
Y317 Phosphorylation PhosphoSitePlus
S322 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T328 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
R331 Methylation PhosphoSitePlus
S333 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648
S334 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18220336, 19664995, ...18669648, 20068231
S338 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...18669648, 20068231
S340 Phosphorylation HPRD   PhosphoSitePlus 20068231
T343 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K432 Sumoylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
S486 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S486 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17287340, 16964243, ...19664995, 18669648, 23186163, 20068231, 17924679
T488 Phosphorylation HPRD 20068231
T489 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 32938750, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
T489 Phosphorylation PhosphoSitePlus
S494 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S495 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S495 Phosphorylation PhosphoSitePlus
S497 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 32938750, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
K498 Sumoylation PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
R509 Methylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
R520 Methylation PhosphoSitePlus
S525 O-Glycosylation GlyGen   IEDB 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 26280087, 31637018, 32574038, 35132862, 32119511, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
R527 Methylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
R571 Methylation PhosphoSitePlus
S584 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S586 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S586 Phosphorylation PhosphoSitePlus
S588 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
S590 O-Glycosylation GlyGen 23301498, 35138101, 30620550, ...31492838, 35289036, 29351928, 29237092, 28657654, 32119511, 31637018, 32574038, 35132862, 31373491, 27655845, 34846842, 33214551, 30379171, 30059200, 35254053, 34019948, 34229054, 20068230
K593 Acetylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R10 C10 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S17 C17 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S227 T227 Biomuta DOID:1612 / breast cancer [ cosmic ]
S227 F227 Biomuta DOID:1319 / brain cancer [ cosmic ]
S246 I246 Biomuta DOID:1324 / lung cancer [ cosmic ]
R249 H249 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R249 C249 Biomuta DOID:4159 / skin cancer [ cosmic ]
R264 H264 Biomuta DOID:363 / uterine cancer [ cosmic ]
R264 C264 Biomuta DOID:363 / uterine cancer [ cosmic ]
R277 L277 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R286 C286 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R286 H286 Biomuta DOID:1612 / breast cancer [ cosmic ]
S313 F313 Biomuta DOID:4159 / skin cancer [ cosmic ]
S322 F322 Biomuta DOID:4159 / skin cancer [ cosmic ]
T328 M328 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T328 S328 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R331 K331 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S334 L334 Biomuta [ cosmic ]
T343 S343 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S517 N517 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R520 H520 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
R527 L527 Biomuta DOID:1324 / lung cancer [ cosmic ]
R571 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S584 F584 Biomuta DOID:4159 / skin cancer [ cosmic ]
S586 L586 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]