Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WXI9 / P66B_HUMAN
Protein Name Transcriptional repressor p66-beta
Gene Name Name: GATAD2B
Synonyms:KIAA1150;
Organism Homo sapiens (Human)

PRO ID PR:Q8WXI9
DAG View
PRO Name transcriptional repressor p66-beta (human)
Definition A transcriptional repressor p66-beta that is encoded in the genome of human.
Short Label hGATAD2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WXI9 (GATAD2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
R10 Methylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus   UniProt 23186163
K30 Ubiquitination PhosphoSitePlus
K33 Sumoylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
T120 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17322306, 21406692, ...23186163, 17081983, 15302935, 18452278, 19651622, 18669648, 19690332, 20068231
S122 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17322306, 21406692, ...23186163, 17081983, 15302935, 18452278, 19651622, 18669648, 19690332, 20068231
S129 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 15302935, 18452278, 19651622, 18669648, 19690332, 19415658, 20068231
S134 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18452278, 18669648, ...19690332, 20068231
S135 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 19690332, 19415658, 20068231
S140 Phosphorylation PhosphoSitePlus
K147 Acetylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus   UniProt 23186163
S213 Phosphorylation HPRD   PhosphoSitePlus 20068231
S223 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
R240 Methylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
R249 Methylation PhosphoSitePlus
R264 Methylation PhosphoSitePlus
R277 Methylation PhosphoSitePlus
K281 Methylation PhosphoSitePlus
R286 Methylation PhosphoSitePlus
C308 S-Nitrosylation dbSNO 26338901
T311 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
R331 Methylation PhosphoSitePlus
S333 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648
S334 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18220336, 19664995, ...18669648, 20068231
S338 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18220336, ...18669648, 20068231
S340 Phosphorylation HPRD   PhosphoSitePlus 20068231
T343 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K432 Sumoylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
S486 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17287340, 16964243, ...19664995, 18669648, 23186163, 20068231, 17924679
T488 Phosphorylation HPRD 20068231
T489 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
K498 Sumoylation PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
R509 Methylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
R520 Methylation PhosphoSitePlus
R527 Methylation PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus
T558 Phosphorylation PhosphoSitePlus
R571 Methylation PhosphoSitePlus
S584 O-Glycosylation PhosphoSitePlus
S586 O-Glycosylation PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
K593 Acetylation PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R10 C10 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1909 / melanoma [ icgc, tcga ]
S17 C17 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K30 * Biomuta DOID:3953 / adrenal gland cancer [ tcga ]
S227 T227 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S246 I246 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
R264 H264 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R264 C264 Biomuta DOID:363 / uterine cancer [ tcga ]
R286 C286 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
R286 H286 Biomuta DOID:1612 / breast cancer [ cosmic ]
T343 N343 Biomuta DOID:363 / uterine cancer [ tcga ]
R527 L527 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
R571 * Biomuta DOID:363 / uterine cancer [ tcga ]
S586 L586 Biomuta DOID:363 / uterine cancer [ icgc, tcga ] DOID:0060119 / pharynx cancer [ cosmic ]