iPTMnet Report for Q8TEJ3 (SH3RF3)
Protein Information
UniProt AC / UniProt ID | Q8TEJ3 / SH3R3_HUMAN |
Protein Name | E3 ubiquitin-protein ligase SH3RF3 |
Gene Name | Name: SH3RF3 Synonyms:POSH2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TEJ3 |
PRO Name | E3 ubiquitin-protein ligase SH3RF3 (human) |
Definition | An E3 ubiquitin-protein ligase SH3RF3 that is encoded in the genome of human. |
Short Label | hSH3RF3 |
Category | organism-gene |
Q8TEJ3 (SH3RF3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
T67 | Phosphorylation | score1 | PhosphoSitePlus | |||
S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
S381 | Phosphorylation | score1 | PhosphoSitePlus | |||
T383 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18767875 | ||
S400 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18220336 | ||
S412 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
T442 | Phosphorylation | score1 | PhosphoSitePlus | |||
S451 | Phosphorylation | score1 | PhosphoSitePlus | |||
T458 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y469 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y473 | Phosphorylation | score1 | PhosphoSitePlus | |||
S542 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
T549 | Phosphorylation | score1 | PhosphoSitePlus | |||
S558 | Phosphorylation | score1 | PhosphoSitePlus | |||
T573 | Phosphorylation | score1 | PhosphoSitePlus | |||
S731 | Phosphorylation | score1 | PhosphoSitePlus | |||
T732 | Phosphorylation | score1 | PhosphoSitePlus | |||
S736 | Phosphorylation | score1 | PhosphoSitePlus | |||
S775 | Phosphorylation | score1 | PhosphoSitePlus | |||
S797 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 18220336 | ||
S881 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T67 | M67 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
S381 | F381 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S412 | R412 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
S437 | F437 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S437 | Y437 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S438 | L438 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
T458 | M458 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S797 | F797 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |