Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TEJ3 / SH3R3_HUMAN
Protein Name E3 ubiquitin-protein ligase SH3RF3
Gene Name Name: SH3RF3
Synonyms:POSH2;
Organism Homo sapiens (Human)

PRO ID PR:Q8TEJ3
DAG View
PRO Name SH3 domain-containing RING finger protein 3 (human)
Definition An SH3 domain-containing RING finger protein 3 that is encoded in the genome of human.
Short Label hSH3RF3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TEJ3 (SH3RF3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T66 Phosphorylation PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
T383 Phosphorylation HPRD   PhosphoSitePlus 18767875
S400 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18220336
S412 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
S542 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T549 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
T573 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S797 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
S881 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T67 M67 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S438 L438 Biomuta DOID:363 / uterine cancer [ tcga ]