iPTMnet Report for Q8TDN4 (CABLES1)
Protein Information
UniProt AC / UniProt ID | Q8TDN4 / CABL1_HUMAN |
Protein Name | CDK5 and ABL1 enzyme substrate 1 |
Gene Name | Name: CABLES1 Synonyms:CABLES; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TDN4 |
PRO Name | CDK5 and ABL1 enzyme substrate 1 (human) |
Definition | A CDK5 and ABL1 enzyme substrate 1 that is encoded in the genome of human. |
Short Label | hCABLES1 |
Category | organism-gene |
Q8TDN4 (CABLES1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R107 | Methylation | score1 | PhosphoSitePlus | |||
S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 23186163, 16964243, ... | ||
S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
T244 | Phosphorylation | score1 | PhosphoSitePlus | |||
S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y260 | Phosphorylation | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 19369195 | ||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
T309 | Phosphorylation | score1 | PhosphoSitePlus | |||
S311 | Phosphorylation | score1 | PhosphoSitePlus | |||
S313 | Phosphorylation | score3 | PhosphoSitePlus Signor | 11733001 | ||
S313 | Phosphorylation | Q00526 (CDK3) | score3 | PhosphoSitePlus Signor | 11733001 | |
T333 | Phosphorylation | score1 | PhosphoSitePlus | |||
S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
T415 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19369195, 18669648, 18691976, ... | ||
S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
S421 | Phosphorylation | score1 | PhosphoSitePlus | |||
S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
S575 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S22 | Phosphorylation | score0 | HPRD | 18691976 | ||
S25 | Phosphorylation | score0 | HPRD | 18691976 | ||
S26 | Phosphorylation | score0 | HPRD | 18691976 | ||
T44 | Phosphorylation | score0 | HPRD | 18691976 | ||
S46 | Phosphorylation | score0 | HPRD | 18691976 | ||
S48 | Phosphorylation | score2 | HPRD | 11733001, 18691976 | ||
S48 | Phosphorylation | P24864 (CCNE1) | score2 | HPRD | 11733001, 18691976 | |
S48 | Phosphorylation | Q00526 (CDK3) | score2 | HPRD | 11733001, 18691976 | |
S108 | Phosphorylation | score0 | HPRD | 18691976 | ||
S113 | Phosphorylation | score0 | HPRD | 18691976 | ||
T150 | Phosphorylation | score0 | HPRD | 18691976, 18669648 | ||
S153 | Phosphorylation | score0 | HPRD | 18691976 | ||
S169 | Phosphorylation | score0 | HPRD | 18691976 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S25 | F25 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S26 | F26 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S46 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S48 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S108 | P108 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S290 | F290 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S291 | F291 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S311 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S313 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S373 | P373 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S432 | C432 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |