iPTMnet Report for Q8TDN4 (CABLES1)
Protein Information
| UniProt AC / UniProt ID | Q8TDN4 / CABL1_HUMAN |
| Protein Name | CDK5 and ABL1 enzyme substrate 1 |
| Gene Name | Name: CABLES1 Synonyms:CABLES; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TDN4 |
| PRO Name | CDK5 and ABL1 enzyme substrate 1 (human) |
| Definition | A CDK5 and ABL1 enzyme substrate 1 that is encoded in the genome of human. |
| Short Label | hCABLES1 |
| Category | organism-gene |
DAG ViewQ8TDN4 (CABLES1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R107 | Methylation | score1 | PhosphoSitePlus | |||
| S109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S168 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18691976, 23186163, 16964243, ... | ||
| S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y260 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S287 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 19369195 | ||
| S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T309 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S311 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S313 | Phosphorylation | Q00526 (CDK3) | score3 | PhosphoSitePlus Signor | 11733001 | |
| T333 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T415 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19369195, 18669648, 18691976, ... | ||
| S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S434 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K515 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S575 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S22 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S25 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S26 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T44 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S46 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S48 | Phosphorylation | Q00526 (CDK3) , P24864 (CCNE1) | score2 | HPRD | 11733001, 18691976 | |
| S108 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S113 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T150 | Phosphorylation | score0 | HPRD | 18691976, 18669648 | ||
| S153 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S169 | Phosphorylation | score0 | HPRD | 18691976 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S25 | F25 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S26 | F26 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S46 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S48 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S108 | P108 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S290 | F290 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S291 | F291 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S311 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S313 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S373 | P373 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S432 | C432 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
