iPTMnet Report for Q8TBZ3 (WDR20)
Protein Information
| UniProt AC / UniProt ID | Q8TBZ3 / WDR20_HUMAN |
| Protein Name | WD repeat-containing protein 20 |
| Gene Name | Name: WDR20 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TBZ3 |
| PRO Name | WD repeat-containing protein 20 (human) |
| Definition | A WD repeat-containing protein 20 that is encoded in the genome of human. |
| Short Label | hWDR20 |
| Category | organism-gene |
Q8TBZ3 (WDR20) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S330 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S350 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S357 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S360 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S432 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692 | ||
| S434 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S448 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T463 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S465 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S483 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K500 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S357 | Phosphorylation | score0 | HPRD | 19651622, 18767875 | ||
| S360 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S432 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
| S434 | Phosphorylation | score0 | HPRD | 18669648, 19664995 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S357 | Phosphorylation | score0 | HPRD | 19651622, 18767875 | ||
| S360 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S432 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
| S434 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
| S569 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S575 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S350 | P350 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S364 | N364 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S445 | G445 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S445 | N445 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| S445 | T445 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T463 | I463 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S465 | L465 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| T499 | I499 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View