iPTMnet Report for Q8TBZ3 (WDR20)
Protein Information
UniProt AC / UniProt ID | Q8TBZ3 / WDR20_HUMAN |
Protein Name | WD repeat-containing protein 20 |
Gene Name | Name: WDR20 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TBZ3 |
PRO Name | WD repeat-containing protein 20 (human) |
Definition | A WD repeat-containing protein 20 that is encoded in the genome of human. |
Short Label | hWDR20 |
Category | organism-gene |
Q8TBZ3 (WDR20) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
S330 | Phosphorylation | score1 | PhosphoSitePlus | |||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
T348 | Phosphorylation | score1 | PhosphoSitePlus | |||
S350 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
S357 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T358 | Phosphorylation | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S364 | Phosphorylation | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
T420 | Phosphorylation | score1 | PhosphoSitePlus | |||
S432 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692 | ||
S434 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
S448 | Phosphorylation | score1 | PhosphoSitePlus | |||
T463 | Phosphorylation | score1 | PhosphoSitePlus | |||
S465 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S483 | Phosphorylation | score1 | PhosphoSitePlus | |||
S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
T499 | Phosphorylation | score1 | PhosphoSitePlus | |||
K500 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S357 | Phosphorylation | score0 | HPRD | 19651622, 18767875 | ||
S360 | Phosphorylation | score0 | HPRD | 19651622 | ||
S432 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S434 | Phosphorylation | score0 | HPRD | 18669648, 19664995 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S357 | Phosphorylation | score0 | HPRD | 19651622, 18767875 | ||
S360 | Phosphorylation | score0 | HPRD | 19651622 | ||
S432 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S434 | Phosphorylation | score0 | HPRD | 18669648, 19664995 | ||
S569 | Phosphorylation | score0 | HPRD | 20068231 | ||
S575 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S350 | P350 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S364 | N364 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
S445 | G445 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S445 | N445 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S445 | T445 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T463 | I463 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S465 | L465 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T499 | I499 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |