iPTMnet Report for Q8TBX8 (PIP4K2C)
Protein Information
UniProt AC / UniProt ID | Q8TBX8 / PI42C_HUMAN |
Protein Name | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma |
Gene Name | Name: PIP4K2C Synonyms:PIP5K2C; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TBX8 |
PRO Name | phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (human) |
Definition | A phosphatidylinositol 5-phosphate 4-kinase type-2 gamma that is encoded in the genome of human. |
Short Label | hPIP4K2C |
Category | organism-gene |
Q8TBX8 (PIP4K2C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330 | ||
S26 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
K27 | Acetylation | score1 | PhosphoSitePlus | |||
K29 | Acetylation | score1 | PhosphoSitePlus | |||
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
K83 | Ubiquitination | score1 | PhosphoSitePlus | |||
K99 | Methylation | score1 | PhosphoSitePlus | |||
Y122 | Phosphorylation | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y217 | Phosphorylation | score1 | IEDB | 35494241 | ||
K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
S349 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
Y368 | Phosphorylation | score1 | PhosphoSitePlus | |||
K390 | Methylation | score1 | PhosphoSitePlus | |||
K390 | Ubiquitination | score1 | PhosphoSitePlus | |||
T417 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S26 | F26 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K83 | N83 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K248 | N248 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |