iPTMnet Report for Q8TBX8 (PIP4K2C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TBX8 / PI42C_HUMAN
Protein Name Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Gene Name Name: PIP4K2C
Synonyms:PIP5K2C;
Organism Homo sapiens (Human)

PRO ID PR:Q8TBX8
DAG View
PRO Name phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (human)
Definition A phosphatidylinositol 5-phosphate 4-kinase type-2 gamma that is encoded in the genome of human.
Short Label hPIP4K2C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TBX8 (PIP4K2C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S26 Phosphorylation PhosphoSitePlus   UniProt 18691976
K27 Acetylation PhosphoSitePlus
K29 Acetylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K99 Methylation PhosphoSitePlus
Y122 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation IEDB 35494241
K248 Ubiquitination PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus   UniProt 18691976
Y368 Phosphorylation PhosphoSitePlus
K390 Methylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 18691976
S208 Phosphorylation HPRD 20068231
Y281 Phosphorylation HPRD 20068231
S328 Phosphorylation HPRD 18691976
S349 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 F26 Biomuta DOID:4159 / skin cancer [ cosmic ]
K83 N83 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K248 N248 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]