iPTMnet Report for Q8NEU8 (APPL2)
Protein Information
| UniProt AC / UniProt ID | Q8NEU8 / DP13B_HUMAN |
| Protein Name | DCC-interacting protein 13-beta |
| Gene Name | Name: APPL2 Synonyms:DIP13B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NEU8 |
| PRO Name | DCC-interacting protein 13-beta (human) |
| Definition | A DCC-interacting protein 13-beta that is encoded in the genome of human. |
| Short Label | hAPPL2 |
| Category | organism-gene |
DAG ViewQ8NEU8 (APPL2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T399 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R555 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K121 | N121 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T346 | R346 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
