Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEU8 / DP13B_HUMAN
Protein Name DCC-interacting protein 13-beta
Gene Name Name: APPL2
Synonyms:DIP13B;
Organism Homo sapiens (Human)

PRO ID PR:Q8NEU8
DAG View
PRO Name DCC-interacting protein 13-beta (human)
Definition A DCC-interacting protein 13-beta that is encoded in the genome of human.
Short Label hAPPL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEU8 (APPL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
R555 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K121 N121 Biomuta DOID:1324 / lung cancer [ cosmic ]