iPTMnet Report for Q8NEU8 (APPL2)
Protein Information
UniProt AC / UniProt ID | Q8NEU8 / DP13B_HUMAN |
Protein Name | DCC-interacting protein 13-beta |
Gene Name | Name: APPL2 Synonyms:DIP13B; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NEU8 |
PRO Name | DCC-interacting protein 13-beta (human) |
Definition | A DCC-interacting protein 13-beta that is encoded in the genome of human. |
Short Label | hAPPL2 |
Category | organism-gene |
Q8NEU8 (APPL2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
T19 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
T346 | Phosphorylation | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
T399 | Phosphorylation | score1 | PhosphoSitePlus | |||
R555 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K121 | N121 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T346 | R346 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |