iPTMnet Report for Q8NER1 (TRPV1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NER1 / TRPV1_HUMAN
Protein Name Transient receptor potential cation channel subfamily V member 1
Gene Name Name: TRPV1
Synonyms:VR1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NER1
DAG View
PRO Name transient receptor potential cation channel subfamily V member 1 (human)
Definition A transient receptor potential cation channel TRPV1 that is encoded in the genome of human.
Short Label hTRPV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NER1 (TRPV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
S117 Phosphorylation Q15139 (PRKD1) neXtProt   PhosphoSitePlus 15471852
S132 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
K161 Acetylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation P12931 (SRC) PhosphoSitePlus   RLIMS-P 16319926
T336 Phosphorylation PhosphoSitePlus
T407 Phosphorylation RLIMS-P 26376215
S502 Phosphorylation Q02156 (PRKCE) , P17612 (PRKACA) , P17252 (PRKCA) neXtProt   PhosphoSitePlus   Signor 11884385, 18701070
T705 Phosphorylation P05771-2 (PRKCB) PhosphoSitePlus 24920628
T773 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S801 Phosphorylation P17252 (PRKCA) , Q02156 (PRKCE) neXtProt   PhosphoSitePlus   Signor 18701070, 11884385
S807 Phosphorylation PhosphoSitePlus
Y814 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S117 Phosphorylation HPRD 12194871, 18452278
S132 Phosphorylation HPRD 18452278
T145 Phosphorylation Q02156 (PRKCE) HPRD 14523239
S502 Phosphorylation Q02156 (PRKCE) HPRD 11884385, 14630912, 14523239
T705 Phosphorylation Q02156 (PRKCE) HPRD 14630912, 14523239
S775 Phosphorylation Q02156 (PRKCE) HPRD 14523239
S801 Phosphorylation Q02156 (PRKCE) HPRD 11884385, 14523239
S821 Phosphorylation Q02156 (PRKCE) HPRD 14523239


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 N6 Biomuta DOID:1324 / lung cancer [ cosmic ]
T196 M196 Biomuta DOID:4159 / skin cancer [ cosmic ]
S775 R775 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]