iPTMnet Report for Q8NER1 (TRPV1)
Protein Information
| UniProt AC / UniProt ID | Q8NER1 / TRPV1_HUMAN |
| Protein Name | Transient receptor potential cation channel subfamily V member 1 |
| Gene Name | Name: TRPV1 Synonyms:VR1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NER1 |
| PRO Name | transient receptor potential cation channel subfamily V member 1 (human) |
| Definition | A transient receptor potential cation channel TRPV1 that is encoded in the genome of human. |
| Short Label | hTRPV1 |
| Category | organism-gene |
DAG ViewQ8NER1 (TRPV1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T7 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S117 | Phosphorylation | score3 | neXtProt PhosphoSitePlus | 15471852 | ||
| S117 | Phosphorylation | Q15139 (PRKD1) | score2 | neXtProt | 15471852 | |
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K161 | Acetylation | score1 | PhosphoSitePlus | |||
| T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y200 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 16319926 | ||
| Y200 | Phosphorylation | P12931 (SRC) | score2 | PhosphoSitePlus | 16319926 | |
| T336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T407 | Phosphorylation | score0 | RLIMS-P | 26376215 | ||
| S502 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor | 11884385, 18701070 | ||
| S502 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 18701070 | |
| S502 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 18701070 | |
| S502 | Phosphorylation | Q02156 (PRKCE) | score3 | neXtProt Signor | 11884385 | |
| T705 | Phosphorylation | score2 | PhosphoSitePlus | 24920628 | ||
| T705 | Phosphorylation | P05771-2 (PRKCB) | score2 | PhosphoSitePlus | 24920628 | |
| T773 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S775 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S780 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S801 | Phosphorylation | score4 | neXtProt PhosphoSitePlus Signor | 18701070, 11884385 | ||
| S801 | Phosphorylation | P17252 (PRKCA) | score2 | PhosphoSitePlus | 18701070 | |
| S801 | Phosphorylation | Q02156 (PRKCE) | score3 | neXtProt Signor | 11884385 | |
| S807 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y814 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S117 | Phosphorylation | score2 | HPRD | 12194871, 18452278 | ||
| S132 | Phosphorylation | score0 | HPRD | 18452278 | ||
| T145 | Phosphorylation | score1 | HPRD | 14523239 | ||
| T145 | Phosphorylation | Q02156 (PRKCE) | score1 | HPRD | 14523239 | |
| S502 | Phosphorylation | score2 | HPRD | 11884385, 14630912, 14523239 | ||
| S502 | Phosphorylation | Q02156 (PRKCE) | score2 | HPRD | 11884385, 14523239 | |
| T705 | Phosphorylation | score2 | HPRD | 14630912, 14523239 | ||
| T705 | Phosphorylation | Q02156 (PRKCE) | score1 | HPRD | 14523239 | |
| S775 | Phosphorylation | score1 | HPRD | 14523239 | ||
| S775 | Phosphorylation | Q02156 (PRKCE) | score1 | HPRD | 14523239 | |
| S801 | Phosphorylation | score2 | HPRD | 11884385, 14523239 | ||
| S801 | Phosphorylation | Q02156 (PRKCE) | score2 | HPRD | 11884385, 14523239 | |
| S821 | Phosphorylation | score1 | HPRD | 14523239 | ||
| S821 | Phosphorylation | Q02156 (PRKCE) | score1 | HPRD | 14523239 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S6 | N6 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T196 | M196 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S775 | R775 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
