Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEG5 / ZSWM2_HUMAN
Protein Name E3 ubiquitin-protein ligase ZSWIM2
Gene Name Name: ZSWIM2
Synonyms:ZZZ2;
Organism Homo sapiens (Human)

PRO ID PR:Q8NEG5
DAG View
PRO Name E3 ubiquitin-protein ligase ZSWIM2 (human)
Definition An E3 ubiquitin-protein ligase ZSWIM2 that is encoded in the genome of human.
Short Label hZSWIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEG5 (ZSWIM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
Y594 Phosphorylation PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T273 A273 Biomuta DOID:1319 / brain cancer [ icgc ]
S542 R542 Biomuta DOID:1324 / lung cancer [ cosmic ]