Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NEG5 / ZSWM2_HUMAN
Protein Name E3 ubiquitin-protein ligase ZSWIM2
Gene Name Name: ZSWIM2
Organism Homo sapiens (Human)

DAG View
PRO Name E3 ubiquitin-protein ligase ZSWIM2 (human)
Definition An E3 ubiquitin-protein ligase ZSWIM2 that is encoded in the genome of human.
Short Label hZSWIM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NEG5 (ZSWIM2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T273 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
Y594 Phosphorylation PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T273 A273 Biomuta DOID:3070 / malignant glioma [ tcga ]
S542 R542 Biomuta DOID:1324 / lung cancer [ cosmic ]