iPTMnet Report for Q8NE63 (HIPK4)
Protein Information
| UniProt AC / UniProt ID | Q8NE63 / HIPK4_HUMAN |
| Protein Name | Homeodomain-interacting protein kinase 4 |
| Gene Name | Name: HIPK4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NE63 |
| PRO Name | homeodomain-interacting protein kinase 4 (human) |
| Definition | A homeodomain-interacting protein kinase 4 that is encoded in the genome of human. |
| Short Label | hHIPK4 |
| Category | organism-gene |
Q8NE63 (HIPK4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K19 | Acetylation | score1 | PhosphoSitePlus | |||
| K27 | Acetylation | score1 | PhosphoSitePlus | |||
| K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T122 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S337 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T381 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T390 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y393 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T122 | P122 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S337 | C337 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T381 | M381 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
| Y392 | C392 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
DAG View