iPTMnet Report for Q8N9V7 (TOPAZ1)
Protein Information
UniProt AC / UniProt ID | Q8N9V7 / TOPZ1_HUMAN |
Protein Name | Protein TOPAZ1 |
Gene Name | Name: TOPAZ1 Synonyms:C3orf77; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N9V7 |
PRO Name | protein TOPAZ1 (human) |
Definition | A protein TOPAZ1 that is encoded in the genome of human. |
Short Label | hTOPAZ1 |
Category | organism-gene |
Q8N9V7 (TOPAZ1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S473 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S515 | Phosphorylation | score1 | PhosphoSitePlus | |||
S516 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y517 | Phosphorylation | score1 | PhosphoSitePlus | |||
S569 | Phosphorylation | score1 | PhosphoSitePlus | |||
S573 | Phosphorylation | score1 | PhosphoSitePlus | |||
S574 | Phosphorylation | score1 | PhosphoSitePlus | |||
S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
T752 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y762 | Phosphorylation | score1 | PhosphoSitePlus | |||
S770 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1131 | Methylation | score1 | PhosphoSitePlus | |||
K1132 | Methylation | score1 | PhosphoSitePlus | |||
S1198 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1370 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1372 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1557 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S569 | Y569 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S573 | A573 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S1198 | F1198 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y1370 | C1370 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y1372 | H1372 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y1557 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] |