iPTMnet Report for Q8N9V7 (TOPAZ1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N9V7 / TOPZ1_HUMAN
Protein Name Protein TOPAZ1
Gene Name Name: TOPAZ1
Synonyms:C3orf77;
Organism Homo sapiens (Human)

PRO ID PR:Q8N9V7
DAG View
PRO Name protein TOPAZ1 (human)
Definition A protein TOPAZ1 that is encoded in the genome of human.
Short Label hTOPAZ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N9V7 (TOPAZ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
Y517 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
T752 Phosphorylation PhosphoSitePlus
Y762 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
K1131 Methylation PhosphoSitePlus
K1132 Methylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus
Y1370 Phosphorylation PhosphoSitePlus
Y1372 Phosphorylation PhosphoSitePlus
Y1557 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S569 Y569 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S573 A573 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1198 F1198 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1370 C1370 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1372 H1372 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y1557 * Biomuta DOID:4159 / skin cancer [ cosmic ]