iPTMnet Report for Q8N4V1 (MMGT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N4V1 / EMC5_HUMAN
Protein Name ER membrane protein complex subunit 5
Gene Name Name: MMGT1
Synonyms:EMC5;
Organism Homo sapiens (Human)

PRO ID PR:Q8N4V1
DAG View
PRO Name ER membrane protein complex subunit 5 (human)
Definition An ER membrane protein complex subunit 5 that is encoded in the genome of human.
Short Label hMMGT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N4V1 (MMGT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K79 Ubiquitination PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
R96 Methylation PhosphoSitePlus
S110 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S120 Phosphorylation PhosphoSitePlus   UniProt 23186163
K122 Ubiquitination PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S109 Phosphorylation HPRD 20068231
S110 Phosphorylation HPRD 18669648
S120 Phosphorylation HPRD 18578522


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K79 M79 Biomuta DOID:5158 / pleural cancer [ cosmic ]
T83 M83 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R96 H96 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S109 T109 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S109 C109 Biomuta DOID:1324 / lung cancer [ cosmic ]
S110 L110 Biomuta DOID:4159 / skin cancer [ cosmic ]
S128 * Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]