iPTMnet Report for Q8N4V1 (MMGT1)
Protein Information
UniProt AC / UniProt ID | Q8N4V1 / EMC5_HUMAN |
Protein Name | ER membrane protein complex subunit 5 |
Gene Name | Name: MMGT1 Synonyms:EMC5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N4V1 |
PRO Name | ER membrane protein complex subunit 5 (human) |
Definition | An ER membrane protein complex subunit 5 that is encoded in the genome of human. |
Short Label | hMMGT1 |
Category | organism-gene |
Q8N4V1 (MMGT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
T80 | Phosphorylation | score1 | PhosphoSitePlus | |||
T83 | Phosphorylation | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
R96 | Methylation | score1 | PhosphoSitePlus | |||
S110 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S120 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K122 | Ubiquitination | score1 | PhosphoSitePlus | |||
S128 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K79 | M79 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] | |
T83 | M83 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
R96 | H96 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S109 | T109 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S109 | C109 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S110 | L110 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S128 | * | Biomuta | DOID:4362 / cervical cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] |