iPTMnet Report for Q8N474 (SFRP1)
Protein Information
| UniProt AC / UniProt ID | Q8N474 / SFRP1_HUMAN |
| Protein Name | Secreted frizzled-related protein 1 precursor |
| Gene Name | Name: SFRP1 Synonyms:FRP,FRP1,SARP2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N474 |
| PRO Name | secreted frizzled-related protein 1 (human) |
| Definition | A secreted frizzled-related protein 1 that is encoded in the genome of human. |
| Short Label | hSFRP1 |
| Category | organism-gene |
DAG ViewQ8N474 (SFRP1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S38 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| N173 | N-Glycosylation | score3 | GlyGen UniProt | 11741940 | ||
| T175 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T183 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T184 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| K223 | Acetylation | score1 | PhosphoSitePlus | |||
| K224 | Acetylation | score1 | PhosphoSitePlus | |||
| K231 | Acetylation | score1 | PhosphoSitePlus | |||
| K239 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T175 | P175 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T184 | M184 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| K223 | T223 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K231 | R231 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
