Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N474 / SFRP1_HUMAN
Protein Name Secreted frizzled-related protein 1 precursor
Gene Name Name: SFRP1
Synonyms:FRP,FRP1,SARP2;
Organism Homo sapiens (Human)

PRO ID PR:Q8N474
DAG View
PRO Name secreted frizzled-related protein 1 (human)
Definition A secreted frizzled-related protein 1 that is encoded in the genome of human.
Short Label hSFRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N474 (SFRP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S38 O-Glycosylation GlyGen 30459171
N173 N-Glycosylation GlyGen   UniProt 11741940
T175 O-Glycosylation GlyGen 30459171
T183 O-Glycosylation GlyGen 30459171
T184 O-Glycosylation GlyGen 30459171
K223 Acetylation PhosphoSitePlus
K224 Acetylation PhosphoSitePlus
K231 Acetylation PhosphoSitePlus
K239 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T175 P175 Biomuta DOID:1612 / breast cancer [ icgc ]
T184 K184 Biomuta DOID:3571 / liver cancer [ icgc ]
T184 M184 Biomuta DOID:4362 / cervical cancer [ tcga ]
K223 T223 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]