iPTMnet Report for Q8N1K5 (THEMIS)
Protein Information
| UniProt AC / UniProt ID | Q8N1K5 / THMS1_HUMAN |
| Protein Name | Protein THEMIS |
| Gene Name | Name: THEMIS Synonyms:C6orf190,C6orf207; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8N1K5 |
| PRO Name | protein THEMIS (human) |
| Definition | A protein THEMIS that is encoded in the genome of human. |
| Short Label | hTHEMIS |
| Category | organism-gene |
Q8N1K5 (THEMIS) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y220 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T222 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K312 | Acetylation | score1 | PhosphoSitePlus | |||
| S316 | O-Glycosylation | score1 | GlyGen | 35008409, 30620550 | ||
| S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K339 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y429 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y540 | Phosphorylation | score2 | PhosphoSitePlus | 23460737 | ||
| Y540 | Phosphorylation | P06239 (LCK) | score2 | PhosphoSitePlus | 23460737 | |
| Y540 | Phosphorylation | P43403 (ZAP70) | score2 | PhosphoSitePlus | 23460737 | |
| Y541 | Phosphorylation | score2 | PhosphoSitePlus | 23460737 | ||
| Y541 | Phosphorylation | P06239 (LCK) | score2 | PhosphoSitePlus | 23460737 | |
| Y541 | Phosphorylation | P43403 (ZAP70) | score2 | PhosphoSitePlus | 23460737 | |
| K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S584 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19690332, 15144186 | ||
| K595 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K606 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S611 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K620 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K586 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y95 | * | Biomuta | DOID:3565 / meningioma [ cosmic ] | |
| K208 | T208 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K208 | E208 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
| Y220 | F220 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K239 | I239 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K339 | N339 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K379 | M379 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| K406 | Q406 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K415 | Q415 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
| K442 | N442 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View