iPTMnet Report for Q8N1K5 (THEMIS)
Protein Information
UniProt AC / UniProt ID | Q8N1K5 / THMS1_HUMAN |
Protein Name | Protein THEMIS |
Gene Name | Name: THEMIS Synonyms:C6orf190,C6orf207; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N1K5 |
PRO Name | protein THEMIS (human) |
Definition | A protein THEMIS that is encoded in the genome of human. |
Short Label | hTHEMIS |
Category | organism-gene |
Q8N1K5 (THEMIS) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y174 | Phosphorylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y220 | Phosphorylation | score1 | PhosphoSitePlus | |||
T222 | Phosphorylation | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
K312 | Acetylation | score1 | PhosphoSitePlus | |||
S316 | O-Glycosylation | score1 | GlyGen | 35008409, 30620550 | ||
S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
K339 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y353 | Phosphorylation | score1 | PhosphoSitePlus | |||
K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
T370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
K406 | Ubiquitination | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y429 | Phosphorylation | score1 | PhosphoSitePlus | |||
K441 | Ubiquitination | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus | |||
K451 | Ubiquitination | score1 | PhosphoSitePlus | |||
K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y540 | Phosphorylation | P06239 (LCK) , P43403 (ZAP70) | score2 | PhosphoSitePlus | 23460737 | |
Y541 | Phosphorylation | P06239 (LCK) , P43403 (ZAP70) | score2 | PhosphoSitePlus | 23460737 | |
K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
S584 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19690332, 15144186 | ||
K595 | Ubiquitination | score1 | PhosphoSitePlus | |||
K606 | Ubiquitination | score1 | PhosphoSitePlus | |||
S611 | Phosphorylation | score1 | PhosphoSitePlus | |||
K620 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K586 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y95 | * | Biomuta | DOID:3565 / meningioma [ cosmic ] | |
K208 | T208 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K208 | E208 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
Y220 | F220 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K239 | I239 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K339 | N339 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K379 | M379 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K406 | Q406 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K415 | Q415 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
K442 | N442 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |