iPTMnet Report for Q8IZY2 (ABCA7)
Protein Information
UniProt AC / UniProt ID | Q8IZY2 / ABCA7_HUMAN |
Protein Name | Phospholipid-transporting ATPase ABCA7 |
Gene Name | Name: ABCA7 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IZY2 |
PRO Name | phospholipid-transporting ATPase ABCA7 (human) |
Definition | A phospholipid-transporting ATPase ABCA7 that is encoded in the genome of human. |
Short Label | hABCA7 |
Category | organism-gene |
Q8IZY2 (ABCA7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N96 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N98 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
K127 | Ubiquitination | score1 | PhosphoSitePlus | |||
S147 | Phosphorylation | score1 | PhosphoSitePlus | |||
S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
N312 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N340 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
S519 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y528 | Phosphorylation | score1 | PhosphoSitePlus | |||
T555 | O-Glycosylation | score1 | GlyGen | 35008409, 29351928 | ||
K932 | Ubiquitination | score1 | PhosphoSitePlus | |||
S949 | Phosphorylation | score1 | PhosphoSitePlus | |||
S958 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1122 | Phosphorylation | score1 | IEDB | 35494241 | ||
N1335 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T1405 | Phosphorylation | score1 | PhosphoSitePlus | |||
N1518 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
T1748 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1844 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2133 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N98 | S98 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S147 | F147 | Biomuta | DOID:4362 / cervical cancer [ icgc ] | |
S182 | R182 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S182 | N182 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S182 | G182 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
N340 | I340 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
N340 | D340 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K411 | N411 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
K932 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S958 | F958 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T1122 | M1122 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
N1335 | D1335 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
N1518 | S1518 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |