Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8IV08 / PLD3_HUMAN
Protein Name Phospholipase D3
Gene Name Name: PLD3
Organism Homo sapiens (Human)

DAG View
PRO Name phospholipase D3 (human)
Definition A phospholipase D3 that is encoded in the genome of human.
Short Label hPLD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8IV08 (PLD3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
Y7 Phosphorylation PhosphoSitePlus
K11 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
N97 N-Glycosylation UniProt 19159218
N132 N-Glycosylation UniProt 19159218
K157 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
T225 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K11 N11 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
N97 S97 Biomuta DOID:2531 / hematologic cancer [ icgc ]
N132 S132 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S216 N216 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
T225 I225 Biomuta DOID:2394 / ovarian cancer [ tcga ]