iPTMnet Report for Q8IV08 (PLD3)
Protein Information
| UniProt AC / UniProt ID | Q8IV08 / PLD3_HUMAN |
| Protein Name | 5'-3' exonuclease PLD3 |
| Gene Name | Name: PLD3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8IV08 |
| PRO Name | 5'-3' exonuclease PLD3 (human) |
| Definition | A 5'-3' exonuclease PLD3 that is encoded in the genome of human. |
| Short Label | hPLD3 |
| Category | organism-gene |
DAG ViewQ8IV08 (PLD3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y7 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K11 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N97 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
| N132 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
| K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N236 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
| S238 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N284 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N387 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K11 | N11 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| K30 | R30 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| N97 | S97 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| N132 | S132 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S216 | N216 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| T225 | I225 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |
