iPTMnet Report for Q7Z2W7 (TRPM8)
Protein Information
| UniProt AC / UniProt ID | Q7Z2W7 / TRPM8_HUMAN |
| Protein Name | Transient receptor potential cation channel subfamily M member 8 |
| Gene Name | Name: TRPM8 Synonyms:LTRPC6,TRPP8; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z2W7 |
| PRO Name | transient receptor potential cation channel subfamily M member 8 (human) |
| Definition | A transient receptor potential cation channel TRPM8 that is encoded in the genome of human. |
| Short Label | hTRPM8 |
| Category | organism-gene |
DAG ViewQ7Z2W7 (TRPM8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score2 | PhosphoSitePlus | 20110357 | ||
| S9 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 20110357 | |
| T17 | Phosphorylation | score2 | PhosphoSitePlus | 20110357 | ||
| T17 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 20110357 | |
| S341 | Phosphorylation | score1 | IEDB | 35494241 | ||
| K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T448 | Phosphorylation | score1 | IEDB | 35494241 | ||
| T503 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y506 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S850 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N934 | N-Glycosylation | score3 | GlyGen UniProt | 17065148 | ||
| S1040 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1041 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T448 | P448 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T448 | A448 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| T503 | M503 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |
