iPTMnet Report for Q7Z2W7 (TRPM8)
Protein Information
UniProt AC / UniProt ID | Q7Z2W7 / TRPM8_HUMAN |
Protein Name | Transient receptor potential cation channel subfamily M member 8 |
Gene Name | Name: TRPM8 Synonyms:LTRPC6,TRPP8; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z2W7 |
PRO Name | transient receptor potential cation channel subfamily M member 8 (human) |
Definition | A transient receptor potential cation channel TRPM8 that is encoded in the genome of human. |
Short Label | hTRPM8 |
Category | organism-gene |
Q7Z2W7 (TRPM8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 20110357 | |
T17 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 20110357 | |
S341 | Phosphorylation | score1 | IEDB | 35494241 | ||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
T448 | Phosphorylation | score1 | IEDB | 35494241 | ||
T503 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y506 | Phosphorylation | score1 | PhosphoSitePlus | |||
S850 | Phosphorylation | score1 | PhosphoSitePlus | |||
N934 | N-Glycosylation | score3 | GlyGen UniProt | 17065148 | ||
S1040 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1041 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T448 | P448 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
T448 | A448 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
T503 | M503 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] |