iPTMnet Report for Q7Z2W7 (TRPM8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z2W7 / TRPM8_HUMAN
Protein Name Transient receptor potential cation channel subfamily M member 8
Gene Name Name: TRPM8
Synonyms:LTRPC6,TRPP8;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z2W7
DAG View
PRO Name transient receptor potential cation channel subfamily M member 8 (human)
Definition A transient receptor potential cation channel TRPM8 that is encoded in the genome of human.
Short Label hTRPM8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z2W7 (TRPM8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 20110357
T17 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 20110357
S341 Phosphorylation IEDB 35494241
K423 Ubiquitination PhosphoSitePlus
T448 Phosphorylation IEDB 35494241
T503 Phosphorylation PhosphoSitePlus
Y506 Phosphorylation PhosphoSitePlus
S850 Phosphorylation PhosphoSitePlus
N934 N-Glycosylation GlyGen   UniProt 17065148
S1040 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T448 P448 Biomuta DOID:1612 / breast cancer [ cosmic ]
T448 A448 Biomuta DOID:1319 / brain cancer [ cosmic ]
T503 M503 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]