iPTMnet Report for Q7L9B9 (EEPD1)
Protein Information
| UniProt AC / UniProt ID | Q7L9B9 / EEPD1_HUMAN |
| Protein Name | Endonuclease/exonuclease/phosphatase family domain-containing protein 1 |
| Gene Name | Name: EEPD1 Synonyms:KIAA1706; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7L9B9 |
| PRO Name | endonuclease/exonuclease/phosphatase family domain-containing protein 1 (human) |
| Definition | An endonuclease/exonuclease/phosphatase family domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hEEPD1 |
| Category | organism-gene |
Q7L9B9 (EEPD1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score1 | UniProt | 20213681 | ||
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S19 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S25 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S106 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T129 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T134 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S154 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S160 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S173 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S421 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| S428 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S554 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R560 | Methylation | score1 | PhosphoSitePlus | |||
| S561 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R569 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S16 | L16 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y70 | C70 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S102 | N102 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S149 | I149 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| S149 | R149 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S160 | R160 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S160 | N160 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S554 | I554 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| R560 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] | |
| R560 | Q560 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] | |
| R569 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View