Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7L9B9 / EEPD1_HUMAN
Protein Name Endonuclease/exonuclease/phosphatase family domain-containing protein 1
Gene Name Name: EEPD1
Synonyms:KIAA1706;
Organism Homo sapiens (Human)

PRO ID PR:Q7L9B9
DAG View
PRO Name endonuclease/exonuclease/phosphatase family domain-containing protein 1 (human)
Definition An endonuclease/exonuclease/phosphatase family domain-containing protein 1 that is encoded in the genome of human.
Short Label hEEPD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7L9B9 (EEPD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 20213681
S10 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus   UniProt 24275569
S19 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus   UniProt 23186163
S31 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 24275569
S112 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
T134 Phosphorylation HPRD   PhosphoSitePlus 20068231
S149 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S173 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S200 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S421 Phosphorylation HPRD   PhosphoSitePlus 20068231
S428 Phosphorylation PhosphoSitePlus   UniProt 23186163
S554 Phosphorylation PhosphoSitePlus
R560 Methylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
R569 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 L16 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y70 C70 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S102 N102 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S149 I149 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S149 R149 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S160 R160 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S160 N160 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S554 I554 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R560 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
R560 Q560 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
R569 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]